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Dynabeads™ Mouse T-Activator CD3/CD28 for T-Cell Expansion and Activation
Brand: Thermo Fisher ScientificDynabeads® Mouse T-Activator CD3/CD28 offers a simple method for activation and expansion of T-cells that does not require feeder cells (antigen-presenting cells) or antigen.
The 4.5 µm diameter, inert, superparamagnetic beads are similar in size to antigen-presenting cells, and are covalently coupled to anti-CD3 and anti-CD28 antibodies.
These two antibodies provide primary and co-stimulatory signals, optimized for efficient T-cell activation and expansion.
Expansion of the T-cell population can be stimulated using recombinant IL-2, and after activation or expansion, the magnetic beads can be easily removed using a DynaMag™ magnet.
Dynabeads® Mouse T-Activator CD3/CD28 is for the activation and expansion of mouse T-cells for research purposes.
Features- Activation of T-cells without the need of feeder cells
- Activated cells that retain in vivo-like function
- Maximal reproducibility without contamination by soluble antibodies or mitogens
- From 100- to 1000-fold T-cell expansion
Specifications
Cell Type
- T Cells (Whole Population)
Clonality
- Monoclonal
Purity or Quality Grade
- Research Grade
Reactivity
- Mouse
Sample Type
- Cell Cultures
- Lymph Node
- Spleen