Dynabeads™ Mouse T-Activator CD3/CD28 for T-Cell Expansion and Activation

Brand: Thermo Fisher Scientific

Dynabeads® Mouse T-Activator CD3/CD28 offers a simple method for activation and expansion of T-cells that does not require feeder cells (antigen-presenting cells) or antigen.

The 4.5 µm diameter, inert, superparamagnetic beads are similar in size to antigen-presenting cells, and are covalently coupled to anti-CD3 and anti-CD28 antibodies. 

These two antibodies provide primary and co-stimulatory signals, optimized for efficient T-cell activation and expansion.

Expansion of the T-cell population can be stimulated using recombinant IL-2, and after activation or expansion, the magnetic beads can be easily removed using a DynaMag™ magnet.

Dynabeads® Mouse T-Activator CD3/CD28 is for the activation and expansion of mouse T-cells for research purposes.
Features
  • Activation of T-cells without the need of feeder cells
  • Activated cells that retain in vivo-like function
  • Maximal reproducibility without contamination by soluble antibodies or mitogens
  • From 100- to 1000-fold T-cell expansion

Specifications

Cell Type

  • T Cells (Whole Population)

Clonality

  • Monoclonal

Purity or Quality Grade

  • Research Grade

Reactivity

  • Mouse

Sample Type

  • Cell Cultures
  • Lymph Node
  • Spleen

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